This medication may rarely cause a severe intestinal condition ( Clostridium difficile -associated diarrhea ) due to a type of resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped. l your doctor right away if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood /mucus in your stool.
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Clarithromycin is used to treat a wide variety of bacterial infections. This medication can also be used in combination with anti-ulcer medications to treat certain types of stomach ulcers. It may also be used to prevent certain bacterial infections. Clarithromycin is known as a macrolide antibiotic. It works by stopping the growth of bacteria.
Before taking clarithromycin, l your doctor or pharmacist if you are allergic to it; or to other macrolide antibiotics (such as erythromycin, azithromycin ); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
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Other medications can affect the removal of clarithromycin from your body, which may affect how clarithromycin works. Examples include rifamycins (such as rifabutin), efavirenz, nevirapine, among others.
Do not use anti-diarrhea products or narcotic pain medications if you have any of these symptoms because these products may make them worse.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
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During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
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Do not share this medication with others.
This medication passes into breast milk. Consult your doctor before breast-feeding.
If you are using this medication to treat an infection, continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection. l your doctor if your condition persists or worsens.
You are encouraged to report negative side effects of prescription drugs to the FDA.
Clarithromycin may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can infrequently result in serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.
The dosage and length of treatment are based on your medical condition and response to treatment. In children, the dosage may also be based on weight.
Clarithromycin can slow down the removal of other medications from your body, which may affect how they work. Examples of affected drugs include apixaban, colchicine, digoxin, some drugs used to treat erectile dysfunction-ED/pulmonary hypertension (such as sildenafil, tadalafil), ergot alkaloids (such as ergotamine, dihydroergotamine), some statin drugs (such as lovastatin, simvastatin), tamsulosin, tolvaptan, ticagrelor, among others.
This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu ). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
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Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. To help you remember, take it at the same times each day.
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l your doctor right away if you have any serious side effects, including: hearing loss, mental/mood changes, muscle weakness, eye problems (such as drooping eyelids, blurred vision ), slurred speech, persistent nausea/vomiting, severe stomach/ abdominal pain, dark urine, yellowing of eyes or skin.
If you are taking this medication to prevent certain bacterial infections, take it exactly as directed by your doctor. Do not stop taking the medication without your doctor's approval. l your doctor if you develop signs of infection such as fever or night sweats.
This medication has been prescribed for your current condition only. Do not use it later for another infection unless your doctor directs you to do so. A different medication may be necessary in that case.
Older adults may be more sensitive to the side effects of this drug, especially hearing loss and QT prolongation (see above).
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
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Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using clarithromycin safely.
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Many drugs besides clarithromycin may affect the heart rhythm (QT prolongation), including amiodarone, dofetilide, pimozide, procainamide, quinidine, sotalol, among others.
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Although most antibiotics probably do not affect hormonal birth control such as pills, patch, or ring, some antibiotics may decrease their effectiveness. This could cause pregnancy. Examples include rifamycins such as rifampin or rifabutin. Be sure to ask your doctor or pharmacist if you should use additional reliable birth control methods while using this antibiotic.
Take this medication by mouth with or without food as directed by your doctor, usually every 12 hours. If stomach upset occurs, you may take it with food or milk.
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Diarrhea, nausea, vomiting, and changes in taste may occur. If any of these effects persist or worsen, l your doctor or pharmacist promptly.
Get medical help right away if you have any very serious side effects, including: severe dizziness, fainting, fast/ irregular heartbeat.
Use of this medication for prolonged or repeated periods may result in oral thrush or a new yeast infection. Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.
COMMON BRAND NAME(S): Biaxin GENERIC NAME(S): CLARITHROMYCIN.
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Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching /swelling (especially of the face/ tongue /throat), severe dizziness, trouble breathing.
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Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using clarithromycin, l your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG ), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).
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Laboratory and/or medical tests (such as cultures, liver or kidney function tests) may be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.
Before using this medication, l your doctor or pharmacist your medical history, especially of: liver disease (including liver problems with past clarithromycin use), kidney disease, a certain type of muscle disease ( myasthenia gravis ).
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at.
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Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Information last revised July 2013. 2013 First Databank, Inc.
If overdose is suspected, contact a poison control center or emergency room immediay. US residents can call their local poison control center at. Canada residents can call a provincial poison control center.
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Clarithromycin may cause live bacterial vaccines (such as typhoid vaccine) not to work as well. Therefore, do not have any immunizations/vaccinations while using this medication without the consent of your doctor.
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