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Lethal dose 50





What is lethal dose 50 (LD50)? definition and meaning

11/17/2014
01:02 | Author: David Perry

Lethal dose 50
What is lethal dose 50 (LD50)? definition and meaning

Definition of lethal dose 50 (LD50): Standard measure of the toxicity of a material that will kill half of the sample population of a specific test animal in a specified.

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The LD50

9/16/2014
01:56 | Author: Emma Coleman

Lethal dose 50
The LD50

The LD50 is the dose that kills half (50%) of the animals tested (LD = "lethal dose"). The animals are usually rats or mice, although rabbits, guinea pigs, hamsters.

The LD 50 is a standardized measure for expressing and comparing the toxicity of chemicals.

The table gives the LD 50 values for some insecticides. In each case, the chemical was fed to laboratory rats. Note that the lower the LD 50, the more toxic the chemical.

The LD 50 is the dose that kills half (50%) of the animals tested (LD = "lethal dose"). The animals are usually rats or mice, although rabbits, guinea pigs, hamsters, and so on are sometimes used.

Even adjusting for the test animal's weight, the LD 50 for one species is often quite different from that for another. Thus any LD 50 value gives only a rough estimate of the risk to humans.

The way in which the chemical is administered also has a marked effect on LD 50 values. The chemical may be fed, injected, applied to the animal's skin, etc., and each method usually generates a different LD 50.

In all these tests, the dose must be calculated relative to the size of the animal. The most common units are milligrams of chemical per kilogram of test animal (mg/kg or ppm ).

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Median lethal dose

7/15/2014
03:34 | Author: Lauren Ross

Lethal dose 50
Median lethal dose

In toxicology, the median lethal dose, LD50 (abbreviation for “Lethal Dose, 50%”), LC50 (Lethal Concentration, 50%) or LCt50 (Lethal Concentration & Time) of.

In toxicology, the median lethal dose, LD 50 (abbreviation for “Lethal Dose, 50%”), LC 50 (Lethal Concentration, 50%) or LCt 50 (Lethal Concentration & Time) of a toxic substance or radiation is the dose required to kill half the members of a tested population after a specified test duration. LD 50 figures are frequently used as a general indicator of a substance's acute toxicity. The test was created by J.W. Trevan in 1927. It is being phased out in some jurisdictions in favor of tests such as the Fixed Dose Procedure ; however the concept, and calculation of the median lethal dose for comparison purposes, is still widely used.

The article content of this page came from Wikipedia and is governed by CC-BY-SA.

The term semilethal dose is occasionally used with the same meaning, particularly in translations from non-English-language texts, but can also refer to a sub lethal dose; because of this ambiguity, it is usually avoided.

The choice of 50% lethality as a benchmark avoids the potential for ambiguity of making measurements in the extremes, and reduces the amount of testing required.

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What does LD-50 mean? - Drugs Forum

5/14/2014
05:32 | Author: Emma Coleman

Ld50 lethal dose
What does LD-50 mean? - Drugs Forum

What is LD-50? LD stands for "Lethal Dose". LD50 is the amount of a material, given all at once, which causes the death of 50% (one half) of a.

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Ld50 - Definition and More from the Free Merriam-Webster Dictionary

3/13/2014
07:50 | Author: David Perry

Lethal dose 50
Ld50 - Definition and More from the Free Merriam-Webster Dictionary

The amount of a toxic agent (as a poison, virus, or radiation) that is sufficient to kill 50 percent of a population of animals usually within a certain time.

What made you want to look up LD50 ? Please l us where you read or heard it (including the quote, if possible).

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