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Lipitor and grapefruit adverse effects





Why You Shouldn39t Mix Grapefruit and Statins - Healthline

6/9/2014
04:48 | Author: David Perry

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Why You Shouldn39t Mix Grapefruit and Statins - Healthline

The major risk of mixing statins and grapefruit is increasing the side effects of the drugs. The FDA reports that this could put you at risk for.

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The furanocoumarins inhibit the efficacy of an important enzyme. This enzyme normally helps your body process the medication you take, balancing out how much of it goes into your bloodstream. Because furanocoumarins hinder this enzyme, larger amounts of the drug persist your bloodstream.

Not everybody with high cholesterol levels needs to take statins. The drug is recommended for people who are at a high risk for heart disease. Individuals with a family history of cardiovascular disease and high cholesterol might need to take statins.

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Lipitor and Grapefruit - HowStuffWorks

4/8/2014
06:56 | Author: Emma Coleman

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Lipitor and Grapefruit - HowStuffWorks

Studies have shown that Lipitor and grapefruit are a bad combination. Lipitor is one of many drugs that has adverse effects when combined with grapefruit.

If you like starting the day with a big glass of refreshing grapefruit juice, that morning tradition will have to be one of the dietary habits you change when you start taking Lipitor. Even though the habit sounds healthy enough, it could have life threatening consequences. Lipitor is one of many drugs that has adverse effects when combined with grapefruit juice.

­When grapefruit juice is consumed, it's metabolized by certain enzymes in the liver -- the same enzymes that break down Lipitor in your body.

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Do Statins and Grapefruit Safely Mix? Health Hub from Cleveland

12/17/2014
02:16 | Author: Lauren Ross

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Do Statins and Grapefruit Safely Mix? Health Hub from Cleveland

When statin takers ingest large amounts of grapefruit, the level of statins in their blood can increase, raising the possibility of side effects.

Problems can occur for those who are sensitive to statin medications or those who have kidney disease or other illnesses. Side effects from grapefruit-statin interaction can be mild, such as muscle and joint pain. Severe side effects include muscle fiber breakdown and kidney failure.

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Statin medications safely lower “bad” LDL cholesterol levels, but eating grapefruit while taking the drugs has been shown to increase the risk of side effects.

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Consumer Updates Grapefruit Juice and Medicine May Not Mix

10/16/2014
12:32 | Author: Emma Coleman

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Consumer Updates Grapefruit Juice and Medicine May Not Mix

Grapefruit juice can affect how well some medicines work, and it “When there is a higher concentration of a drug, you tend to have more adverse events. Zocor (simvastatin), Lipitor (atorvastatin) and Pravachol (pravastatin).

FDA has required some prescription drugs to carry labels that warn against consuming grapefruit juice or fresh grapefruit while using the drug, says Huang. And the agency’s current research into drug and grapefruit juice interaction may result in label changes for other drugs as well. back to top.

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“Grapefruit juice reduces the absorption of fexofenadine,” says Huang, decreasing the effectiveness of the drug. Fexofenadine (brand name Allegra) is available in both prescription and non-prescription forms to relieve symptoms of seasonal allergies.

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Statins and Grapefruit Drug Interactions - Cholesterol - About.com

8/15/2014
02:00 | Author: David Perry

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Statins and Grapefruit Drug Interactions - Cholesterol - About.com

Although statins can greatly lower cholesterol levels, statins and grapefruit wondering how long it takes before you'll see this adverse effect.

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When grapefruit juice is consumed at or around the time you take your statin, the components in grapefruit prevent these enzyme systems from breaking down the drug, causing the drug to accumulate in high amounts in the body. This can be very dangerous and can cause a variety of health problems, such as liver damage or a rare condition called rhabdomyolysis (severe muscle and kidney damage).

Some scientists think that this may be due to the fact that these statins are not broken down by the same enzymes.

Although eating fruit may seem harmless, drinking a glass of grapefruit juice or eating a grapefruit around the time you take your statin may be deadly.

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Ando H, Tsuruoka S, Yanagihara H et al.

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