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Long term effects of zolpidem





Differential effects of short- and long-term zolpidem - Nature

8/16/2014
06:20 | Author: David Perry

Long term effects of zolpidem
Differential effects of short- and long-term zolpidem - Nature

Differential effects of short- and long-term zolpidem treatment on recombinant α1β2γ2s subtype of GABAA receptors in vitro. Josipa Vlainić1.

Correspondence: Josipa Vlaini ć

Zolpidem was a generous gift from Pliva (Zagreb, Croatia). flunitrazepam (specific activity 87 Ci/mmol) was purchased from Amersham Biosciences UK Ltd. Culture medium, antibiotics, fetal bovine serum and other chemicals were supplied from Invitrogen/Gibco (Grand Island, NY, USA).

It has been supposed that drugs with a high selectivity for α 1 containing receptors have fewer side effects compared to classical benzodiazepines. Although chemically different than benzodiazepines, zolpidem elicited many side effects similar to that of benzodiazepines.

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