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Mechanism of action definition





Mechanism of action - Wikipedia, the free encyclopedia

12/25/2014
07:17 | Author: Kayla Henderson

Mechanism of action definition
Mechanism of action - Wikipedia, the free encyclopedia

In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its.

For example, the mechanism of action of aspirin involves irreversible inhibition of the enzyme cyclooxygenase, therefore suppressing the production of prostaglandins and thromboxanes, thereby reducing pain and inflammation. However, some drug mechanisms of action are still unknown. For example, phenytoin is used to treat symptoms of epileptic seizures, but the mechanism by which this is achieved is still unknown, despite the fact that the drug has been in use for many years.

In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect. A mechanism of action usually includes mention of the specific molecular targets to which the drug binds, such as an enzyme or receptor. Receptor sites have specific affinities for drugs based on the chemical structure of the drug, as well as the specific action that occurs there. Drugs that do not bind to receptors produce their corresponding therapeutic effect by simply interacting with chemical or physical properties in the body. Common examples of drugs that utilize this method are antacids and laxatives.

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Mechanism of Action - Definition and Examples

10/24/2014
05:26 | Author: Emma Coleman

Mechanism of action definition
Mechanism of Action - Definition and Examples

What is a mechanism of action, and how is mechanism of action related to the treatment of medical and mental health conditions? Learn the.

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Examples: One of the likely the mechanisms of action of a selective serotonin reuptake inhibitor (SSRI; a type of antidepressant medication) is the inhibition of reuptake of the neurotransmitter serotonin at the synapse, which increases the availability of serotonin in the brain.

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Updated April 30, 2014. Written or reviewed by a board-certified physician. See About.com's Medical Review Board. Definition:

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Also Known As: mode of action.

For many medications, particularly psychotropic medications, the specific mechanism of action is unknown. Similarly, the mechanism of action for most psychosocial interventions is unknown. (I.e., we do not know what specific therapeutic interventions produce the change when someone's symptoms are improved in psychotherapy.).

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The mechanism of action of a medication is the specific biological process through which the medication causes the reduction in symptoms. The mechanism of action of a psychosocial intervention (for example, psychotherapy) is the specific intervention that produces change in the client's symptoms.

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Mechanism of action refers to the process through which some type of treatment or intervention has an effect on the condition in question.

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Mechanism of action - definition of mechanism of action by The Free

8/23/2014
03:11 | Author: Brandon Powell

Mechanism
Mechanism of action - definition of mechanism of action by The Free

N. 1. (Medicine, Biochemistry) The mechanism{2} by which a pharmacologically active substance produces an effect on a living organism or in a biochemical.

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Mechanism of drug action - definition of Mechanism of drug action

6/22/2014
01:28 | Author: Emma Coleman

Stilnox side effects
Mechanism of drug action - definition of Mechanism of drug action

N. 1. (Medicine, Biochemistry) The mechanism{2} by which a pharmacologically active substance produces an effect on a living organism or in a biochemical.

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Toward the definition of the mechanism of action of silymarin

4/21/2014
01:25 | Author: Kayla Henderson

Mechanism of action definition
Toward the definition of the mechanism of action of silymarin

Integr Cancer Ther. 2007 Jun;6(2):120-9. Toward the definition of the mechanism of action of silymarin: activities related to cellular protection from toxic damage.

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Silymarin, the active extract from milk thistle, has been extensively used in patients with liver disease of different etiology. Although silymarin is a complex of 7 flavonolignans and polyphenols, silibinin is usually regarded as the most active component. In vitro and in vivo studies indicate that silymarin and silibinin protect the liver from oxidative stress and sustained inflammatory processes, mainly driven by Reactive Oxygen Species (ROS) and secondary cytokines. Oxidative stress and inflammation are also involved in cellular damage of many other tissues and their role in the development and toxic reactions in patients receiving cancer therapies is established. The protective effects of silymarin and silibinin, demonstrated in various tissues, suggest a clinical application in cancer patients as an adjunct to established therapies, to prevent or reduce their toxicity. Here we discuss the possible mechanism of the protective action of silymarin and silibinin, focusing on cancer therapies as agents causing cellular damage.

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