Pregnancy risk category B.
⊘ Indications and dosages ➣ Insomnia.
• Hypersensitivity to drug.
Drug-behaviors. Alcohol use: increased CNS depression.
GI: nausea, vomiting, diarrhea, dry mouth.
Drug-drug. Antihistamines, opioid analgesics, phenothiazines, sedative-hypnotics, tricyclic antidepressants: increased CNS depression.
• Monitor for physical and psychological drug dependence. Watch for drug hoarding. • Assess for adverse reactions, including confusion, ataxia, and amnesia.
Use cautiously in: • pulmonary disease, hepatic or severe renal impairment • history of psychiatric illness, suicide attempt, or substance abuse • elderly or debilitated patients • pregnant or breastfeeding patients • children (safety not established).
• l patient to take immediay before bedtime (and not after a meal), because it works quickly. • Advise patient to take only when he's able to get a full night's sleep (7 to 8 hours) before he needs to be active again. • Stress that drug is meant only for short-term use (7 to 10 days). • l patient rebound insomnia may occur for 1 to 2 nights after he discontinues drug. • Inform patient that drug may cause amnesia, drowsiness, and a drugged feeling the next day. • Caution patient to avoid driving and other hazardous activities while under drug's influence. • As appropriate, review all other significant adverse reactions and interactions, especially those related to the drugs, herbs, and behaviors mentioned above.
Tablets: 5 mg, 6.25 mg, 10 mg, 12.5 mg.
Ambien, Ambien CR, Stilnoct (UK), Tovalt ODT Pharmacologic class: Imidazopyridine Therapeutic class: Sedative-hypnotic.
Rifampin: decreased zolpidem efficacy.
• Hepatic impairment • Elderly or debilitated patients.
EENT: diplopia, abnormal vision.
• Long-term treatment of insomnia • Insomnia related to selective serotonin reuptake inhibitors • Postoperative sedation.
Other: hypersensitivity reaction, physical or psychological drug dependence, drug tolerance.
Drug-herbs. Chamomile, hops, kava, skullcap, valerian: increased CNS depression.
Controlled substance schedule IV.
Depresses CNS by binding to gamma-aminobutyric acid receptors.
• Don't give with or immediay after a meal. • Know that dosage may need to be decreased if patient's receiving other CNS depressants.
Adults: 10 mg P.O. (Ambien) or 12.5 mg P.O. (Ambien CR) immediay before bedtime.
Ketoconazole, ritonavir: increased blood level and enhanced effects of zolpidem.
CNS: amnesia, ataxia, confusion, euphoria, vertigo, daytime drowsiness, dizziness, drugged feeling.
What is zolpidem tartrate