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Zolpidem and sleep apnea





Ambien safe for OSA sufferers? - Sleep Apnea Support Forum

11/15/2014
04:23 | Author: Nick Jenkins

Zolpidem and zopiclone
Ambien safe for OSA sufferers? - Sleep Apnea Support Forum

When I scheduled my sleep study, the sleep center suggested I get a prescription for an Ambien tablet to take so that I would actually sleep for.

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Effect of zolpidem on the efficacy of continuous positive airway

11/14/2014
02:14 | Author: Lauren Ross

Alcohol and zolpidem
Effect of zolpidem on the efficacy of continuous positive airway

STUDY OBJECTIVE: Assess the effect of the hypnotic zolpidem on the efficacy of nasal PATIENTS: 16 patients with severe obstructive sleep apnea (apnea+.

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Sleep architecture, apnea + hypopnea index, arterial oxygen saturation.

Randomized double blind placebo controlled, cross-over study.

Assess the effect of the hypnotic zolpidem on the efficacy of nasal continuous positive airway pressure for treatment of Obstructive Sleep Apnea.

Three sleep studies were performed over three consecutive weeks. On night one the pressure level required to prevent apnea, hypopnea, and snoring was determined. On the second and third study nights, either placebo (P) or 10 mg of zolpidem (Z) was given (random order) and subjects slept on the CPAP level determined on the first night.

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Veterans Administration Medical Center.

Acute administration of zolpidem 10 mg does not impair the efficacy of an effective level of CPAP in patients with severe obstructive sleep apnea.

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16 patients with severe obstructive sleep apnea (apnea+ hypopnea index > 30/hr), on CPAP therapy for at least 6 months.

The sleep architecture was similar on the placebo and zolpidem nights except for a decrease in the sleep latency ( P: 23.5 +/- 4.7; Z: 13.1 +/- 3.3 minutes, P < 0.02) and a small decrease in the arousal index (P < 0.03) on zolpidem nights. The was no significant difference between placebo and zolpidem nights in the apnea + hypopnea index (P: 4.8 +/- 1.4 versus Z : 2.7 +/- 0.47 events/hour), oxygen desaturation index (1.46 +/- 0.53 versus 0.81 +/- 0.29 desaturations/hour), or the lowest SaO2 (91.4 +/- 0.6 versus 91.0 +/- 0.7%).

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Zolpidem-polysomnographic study of the effect of a new hypnotic

9/13/2014
12:29 | Author: Nick Jenkins

Alcohol and zolpidem
Zolpidem-polysomnographic study of the effect of a new hypnotic

Pharmacol Biochem Behav. 1988 Apr;29(4):807-9. Zolpidem-polysomnographic study of the effect of a new hypnotic drug in sleep apnea syndrome. Cirignotta F.

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Clinical studies have shown that zolpidem, an original imidazopyridine derivative, induces and maintains sleep and does not have daytime side-effects. Polysomnography has revealed that this drug has several interesting qualities that benzodiazepines do not possess: stages 3-4 increase, stage 2 is unchanged or slightly reduced and no abnormal changes are detected on the EEG tracing. Like benzodiazepines, zolpidem slightly reduces REM sleep. The Multiple Sleep Latency Test confirmed that the drug does not cause daytime drowsiness. All the hypnotic drugs studied up to now worsen heavy snoring and obstructive sleep apnea syndrome. A controlled double blind cross-over trial assessed the effects of a single dose of zolpidem 20 mg on nocturnal breathing in patients with mild forms of sleep apnea syndrome. The results indicate that, at this dose, the drug does not overcome the existing contraindications to the use of hypnotics in this syndrome.

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CPAP Community - View topic - Ambien Appears to Remedy Central

7/12/2014
02:48 | Author: David Perry

Alcohol and zolpidem
CPAP Community - View topic - Ambien Appears to Remedy Central

SALT LAKE CITY, June 22 — The sedative Ambien (zolpidem) appears to reduce the symptoms of central sleep apnea, according to a small.

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Ambien for sleep and side effects - Ray Sahelian, M.D

5/11/2014
04:45 | Author: Kayla Henderson

Alcohol and zolpidem
Ambien for sleep and side effects - Ray Sahelian, M.D

They found, however, that treatment with Ambien before bedtime made no difference for the 72 men the study followed. Obstructive sleep apnea is a breathing.

About 30 million people in the United States take sleep medications, according to the American Academy of Sleep Medicine. By some counts that is a 50 percent jump since the beginning of the decade.

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