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Sublingual zolpidem (Edluar Sublinox)

12/21/2014
04:14 | Author: Emma Coleman

Ambien insomnia
Sublingual zolpidem (Edluar Sublinox)

A sublingual orally disintegrating tablet formulation of zolpidem (Edluar; Sublinox) has been developed to provide a more rapid onset of action than oral.

Zolpidem is a non-benzodiazepine hypnotic used in the short-term treatment of insomnia. A sublingual orally disintegrating tablet formulation of zolpidem (Edluar; Sublinox) has been developed to provide a more rapid onset of action than oral immediate-release zolpidem. Sublingual zolpidem has demonstrated bioequivalence to oral zolpidem. In a randomized, double-blind, double-dummy, crossover, multi-centre study in adult patients with primary insomnia (n = 70), a single 10-mg dose of sublingual zolpidem significantly reduced latency to persistent sleep (primary endpoint) compared with a single 10-mg dose of oral immediate-release zolpidem. Sleep-onset latency and latency to stage 1 sleep were also significantly shorter with sublingual zolpidem than with oral zolpidem. Moreover, compared with the oral formulation, sublingual zolpidem was noninferior in terms of total sleep time and did not significantly differ in terms of duration of wake after sleep onset. Sublingual zolpidem was generally well tolerated in this trial, with most adverse events being of mild or moderate severity. The overall tolerability profile of sublingual zolpidem was similar to that of oral zolpidem.

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Zolpidem Onset Effects - Bluelight

10/20/2014
02:32 | Author: Emma Coleman

Ambien insomnia
Zolpidem Onset Effects - Bluelight

I just had 20mg Zolpidem 15 minutes ago, and the last couple minutes have been manic! It's like induced mania, motor control is compromised.

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8/19/2014
12:02 | Author: David Perry

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6/18/2014
02:16 | Author: Lauren Ross

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Sublingual zolpidem is more effective than oral zolpidem in initiating

4/17/2014
04:10 | Author: David Perry

Ambien insomnia
Sublingual zolpidem is more effective than oral zolpidem in initiating

Sublingual zolpidem is more effective than oral zolpidem in initiating early onset of sleep in the post-nap model of transient insomnia: A polysomnographic study.

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