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Zolpidem pharmacology





Zolpidem an update of its pharmacology, therapeutic efficacy and

11/13/2014
02:03 | Author: Nick Jenkins

Zolpidem pharmacology
Zolpidem an update of its pharmacology, therapeutic efficacy and

Zolpidem: an update of its pharmacology, therapeutic efficacy and tolerability in the treatment of insomnia. Holm KJ, Goa KL. Zolpidem is an imidazopyridine.

Zolpidem is effective and well tolerated in patients with insomnia, including the elderly. Studies have shown that zolpidem generally has similar efficacy to other hypnotics including benzodiazepines and zopiclone. Zolpidem appears to have minimal next-day effects on cognition and psychomotor performance when administered at bedtime. In addition, there is little evidence of tolerance to the hypnotic effects of zolpidem, or rebound insomnia or withdrawal symptoms after discontinuation of the drug when it is given as recommended (10 mg/day for < 1 month) or over longer periods.

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National Center for Biotechnology Information, U.S.

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Ambien (Zolpidem) - Description and Clinical Pharmacology

9/12/2014
12:54 | Author: Lauren Ross

Zolpidem pharmacology
Ambien (Zolpidem) - Description and Clinical Pharmacology

DESCRIPTION. Ambien (zolpidem tartrate) is a non-benzodiazepine hypnotic of the imidazopyridine class and is available in 5 mg and 10 mg strength tablets.

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Behavioral Pharmacology of Zolpidem Relative to Benzodiazepines

7/11/2014
02:31 | Author: Nick Jenkins

Zolpidem pharmacology
Behavioral Pharmacology of Zolpidem Relative to Benzodiazepines

Abstract. Zolpidem, an imidazopyridine that purportedly binds selectively to certain GABAA receptor subtypes, is the most commonly prescribed hypnotic.

Volume 61, Issue 3, November 1998, Pages 253–269 No articles found.

This article has not been cited. No articles found.

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The behavioral pharmacology of zolpidem evidence for - Springer

5/10/2014
04:28 | Author: David Perry

Zolpidem pharmacology
The behavioral pharmacology of zolpidem evidence for - Springer

The behavioral pharmacology of zolpidem: evidence for the functional significance of α1-containing GABA A receptors. Amanda C. Fitzgerald.

The literature reviewed indicates that α1- GABA A Rs play a principle role in mediating the hypothermic, ataxic-like, locomotor- and memory-impairing effects of zolpidem and BZs. Evidence also suggests that α1- GABA A Rs play partial roles in the hypnotic, EEG sleep, anticonvulsant effects, and anxiolytic-like of zolpidem and diazepam.

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Ambien Clinical Pharmacology

3/9/2014
06:45 | Author: Kayla Henderson

Zolpidem pharmacology
Ambien Clinical Pharmacology

In contrast to the benzodiazepines, which nonselectively bind to and activate all omega receptor subtypes, zolpidem in vitro binds the (1) receptor preferentially.

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